Django ORM (Object-Relational Mapping) is a powerful feature of the Django web framework that simplifies database interactions for developers. By allowing users to work with databases using Python code instead of raw SQL, Django ORM abstracts the complexities of database management. It represents database tables as Python classes, with each table row corresponding to an instance of a class. This approach not only streamlines the process of creating, retrieving, updating, and deleting data but also enhances code readability and maintainability. Overall, Django ORM is essential for efficient database handling in web applications built with Django.