Tuples in Python are a built-in data structure that allows you to store multiple items in a single, ordered, and immutable collection. Unlike lists, tuples cannot be modified after their creation, making them ideal for storing fixed data. They are defined using parentheses and can contain heterogeneous data types, including integers, strings, and even other tuples. Tuples support indexing, allowing you to access elements using their position, and they can also hold duplicate values. Their immutability and ability to group related data make tuples a versatile choice for various programming scenarios, such as function arguments and data unpacking.